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日期:2020-08-19浏览:768次
【文献标题】Alogliptin prevents diastolic dysfunction and preserves left ventricular mitochondrial function in diabetic rabbits
【作者】Xiaowei Zhang,Zhiwei Zhang,Yajuan Yang,et.al
【作者单位】天津医科大学第二医院(Second Hospital of Tianjin Medical University)
【文献中引用产品】
兔胰高血糖素(Glucagon)ELISA试剂盒
兔8羟基脱氧鸟苷(8-OHdG)ELISA试剂盒
【关键词】Dipeptidyl peptidase-4 inhibitors, Diabetic cardiomyopathy, Diabetes mellitus, Mitochondrial function, Mitochondrial biogenesis
【DOI】doi.org/10.1186/s12933-018-0803-z
【影响因子(IF)】9.5
【出版期刊】《BMC BIOLOGY》
【产品原文引用】
Serum biochemical, infammatory oxidative stress measurements
Blood samples collected were used for serum biochemical examination, including fasting glucose, total cholesterol, triglyceride, low-density lipoprotein cholesterol (LDL-c), high density lipoprotein cholesterol (HDL-c) and creatinine level by full automatic biochemical analyzer. Fasting insulin and GLP-1 level were assessed using Rabbit Insulin ELISA Kit (Wuhan Huamei Biological Engineering Co., Ltd, Hubei Province, China) and Rabbit Glucagon Like Peptide-1 ELISA Kit (Shanghai Huding Biological Technology Co., Shanghai, China) according to the manufacturer’s instructions respectively. Serum oxidative stress related markers Lipid Peroxidation Malondialdehyde (MDA) and 8-hydroxy-2 deoxyguanosine (8-OHdG) were assessed by MDA Assay Kit (Nanjing Jianchen Bioengineering Institute, Jiangsu Province, China) and Rabbit 8-OHdG ELISA Kit (Shanghai Huding Biological Technology Co., Shanghai, China). Serum antioxidant enzyme superoxide Jianchen Bioengineering Institute, Jiangsu Province, China). And the infammation maker high-sensitivity C-reactive protein (hs-CRP) level was detected using Rabbit hs-CRP ELISA KIT (Wuhan Huamei Biological Engineering Co., Ltd, Hubei Province, China).
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